1. Ukulungiswa kwesitimu esihlanzekile ezitshalweni ze-biopharmaceutical
Kusukela kusigaba sokusebenza, isistimu ye-steam ehlanzekile iqukethe izingxenye ezimbili: iyunithi yokulungiselela kanye neyunithi yokusabalalisa. Amajeneretha esitimu ahlanzekile ngokuvamile asebenzisa isitimu sasembonini njengomthombo wokushisa, futhi asebenzise izishintshi zokushisa namakholomu ahwamukayo ukushintshanisa ukushisa futhi akhiphe isitimu, ngaleyo ndlela enze ukuhlukaniswa okusebenzayo komhwamuko ukuze kutholakale isitimu esimsulwa. Njengamanje, izindlela ezimbili ezijwayelekile zokulungiselela isitimu ezihlanzekile zihlanganisa ukuhwamuka okubilayo kanye nokuhwamuka kwefilimu.
Ijeneretha yesitimu ehwamukayo ebilayo iyindlela evamile yokuhwamuka kukabhayela. Amanzi aluhlaza ayafudunyezwa bese eguqulwa abe isitimu esixutshwe namaconsi amancane ambalwa. Amaconsi amancane ahlukaniswa amandla adonsela phansi futhi aphinde ahwamuke. Isitimu singena engxenyeni yokuhlukanisa ngomshini oklanywe ngokukhethekile we-wire mesh bese singena ohlelweni lokusabalalisa ngepayipi eliphumayo. Amaphuzu ahlukahlukene okusetshenziswa.
Amajeneretha esitimu ahwamukayo efilimu ngokuvamile asebenzisa ikholomu efanayo yokuhwamuka njengekholomu yokuhwamuka komthelela wokuqala womshini wamanzi acwengekile anemiphumela eminingi. Isimiso esiyinhloko ukuthi amanzi aluhlaza ashiswe ngaphambilini angena phezulu kwe-evaporator ngepompo yomjikelezo futhi asakazwe ngokulinganayo emgqeni wokuhwamuka ngokusebenzisa idivayisi yepuleti lokusabalalisa. Ukugeleza kwamanzi okufana nefilimu kwakhiwa ku-tube, futhi ukushintshaniswa kokushisa kwenziwa nge-steam yezimboni; ifilimu ewuketshezi eshubhuni ihwamuka ngokushesha ibe isitimu, futhi umusi uyaqhubeka nokuvunguza phezulu ku-evaporator, udlula emshinini wokuhlukanisa uketshezi oluwuketshezi, futhi uba umusi omsulwa osuka ku-pure I-outlet yesitimu iyaphuma, futhi uketshezi olusele lufakwe ngaphakathi. I-pyrogen ikhishwa ngokuqhubekayo ngaphansi kwekholomu. Inani elincane lesitimu esimsulwa liyapholiswa futhi liqoqwe yisampuli yokufingqa, futhi ukuhanjiswa kuhlolwa ku-inthanethi ukuze kunqunywe ukuthi ingabe isitimu esimsulwa sifanelekile yini.
2. Ukusatshalaliswa kwesitimu esihlanzekile ezitshalweni ze-biopharmaceutical
Iyunithi yokusabalalisa ikakhulukazi ihlanganisa inethiwekhi yamapayipi okusabalalisa kanye nezindawo zokusebenzisa. Umsebenzi wayo oyinhloko ukuthutha isitimu esihlanzekile siye ezindaweni ezidingekayo zenqubo ngesilinganiso esithile sokugeleza ukuze kuhlangatshezwane nezidingo zokugeleza, ingcindezi nezinga lokushisa, nokugcina ikhwalithi yesitimu esihlanzekile ngokuhambisana nezidingo ze-pharmacopoeia kanye ne-GMP.
Zonke izingxenye zesistimu yokusabalalisa isitimu esihlanzekile kufanele zidonse amanzi, amapayipi kufanele abe nemithambeka efanelekile, ivalvu yokuhlukanisa okulula ukuyisebenzisa kufanele ifakwe endaweni yokusetshenziswa futhi kufanele kufakwe isicupho sesitimu esiqondisiwe ekugcineni. Njengoba izinga lokushisa elisebenzayo lesistimu yesitimu ehlanzekile liphezulu kakhulu, ezimbonini ze-biopharmaceutical, isistimu yepayipi yesitimu eklanywe kahle ngokwayo inomsebenzi wokuzibulala inzalo, futhi ingozi yokungcoliswa kwamagciwane incane uma kuqhathaniswa.
Amasistimu okusabalalisa isitimu ahlanzekile kufanele alandele izinqubo ezinhle zobunjiniyela ezifanayo futhi ngokuvamile asebenzise ibanga elingu-304, 316, noma elingu-316L lensimbi engagqwali elingagqwali, noma ipayipi elidonswe ngokuphelele. Njengoba ukuhlanza isitimu kuwukuzibulala ngokwakho, ukupholisha kwendawo akusona isici esibalulekile futhi amapayipi kufanele akhelwe ukuvumela ukunwetshwa okushisayo nokugeleza kwe-condensate.